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Pathology 48 , 177187 (2016)

No difference in maximal respiratory capacity was observed with either TNF- or NR co-treatment (Fig 2F)

FIGURE 5 Ferroptosis, a regulatory cell death mode, is characterized by iron-dependent and lipid peroxide (LPO) accumulation, proposed by 2+ , which can produce OH through the Fenton reaction, and then react with polyunsaturated fatty acids in the plasma membrane to produce ROS, resulting in iron-regulated death